-
Cellular Predictive Factors of Drug Resistance in Non-Small Cell Lung Carcinomas
Resistance to chemotherapy is a major source of failure in cancer treatment. A l
-
p53Transfectants in Ovarian Cancer
The tumor suppressor gene tp53 is mutated, deleted, or rearranged in more than 5
-
The Guideline of the Design and Validation of MiRNA Mimics
The miRNA mimic technology (miR-Mimic) is an innovative approach for gene silenc
-
Optical Proteolytic Beacons for In Vivo Detection of Matrix Metalloproteinase Activity
The exuberant expression of proteinases by tumor cells has long been associated
-
In Vivo Vascular Leakage Assay
This chapter describes the methods for measuring the increase in vascular permea
-
The Identification of Colon Cancer Susceptibility Genes by Using Genome-Wide Scans
Recent studies have indicated that in ∼35% of all colorectal cancer (CRC) cases,
-
Immunocompetent Mouse Model of Ovarian Cancer for In Vivo Imaging
Syngeneic and transgenic mouse models are important tools for the study of the b
-
Stability and Ubiquitination of the Tumor Suppressor Protein p53
The ubiquitin-dependent proteolysis pathway constitutes a major pathway in the c
-
The Clinical Use of PET/CT in the Evaluation of Melanoma
Positron emission tomography combined with computed tomography (PET/CT) has emer
-
Adhesion of Tumor Cells to Matrices and Endothelium
Cell adhesion is a process fundamental to tumor metastasis. Egress of cells from
-
Representational Difference Analysis of Gene Expression
The technique of representational difference analysis (RDA) allows the selective
-
Signal Transduction Study Using Gene-Targeted Embryonic Stem Cells
Gene targeting is one of the most powerful tools to define the role of signaling
-
Characterization of Nonmalignant and Malignant Prostatic Stem/Progenitor Cells by Hoechst Side Popul
Recent technical progress in the field of cancer stem/progenitor cell research r
-
Designing Plasmid Vectors
Nonviral gene therapy vectors are commonly based on recombinant bacterial plasmi
-
Immunohistochemistry and In Situ Hybridization in Pancreatic Neoplasia
There are many types of pancreatic neoplasms. Pathologic examination, which incl
