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Identification of Tumor-Associated Antigens as Diagnostic and Predictive Biomarkers in Cancer
Many studies demonstrated that cancer sera contain antibodies which react with a
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Detection of Low Levels of DNA Fragmentation in Ovarian Tumor Cell Lines
The techniques presented in this chapter describe the experimental procedure for
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Polymerase Chain Reaction Based Methods for Assessing Chimerism Following Allogeneic Bone Marrow Tra
It is important to be able to assess the contribution of donor cells to the graf
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Genetic Modification of Cell Lines to Enhance Their Metastatic Capability
Metastasis is the final step in tumor progression from a benign cell to a fully
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Tumor Necrosis Factor as a Pharmacological Target
Tumor necrosis factor (TNF) was originally described as a molecule with antitumo
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Practical Methods for Tissue Microarray Construction
The tissue microarray (TMA) of Kononen et al. is an extension of an idea origina
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Quantitative, Competitive RT-PCR Analysis of Biomarkers in the Study of Neoplasia
The current status of the evaluation of many neoplasias (e.g., carcinoma of the
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Detection of Chromosomal Aberrations in Lung Tissue and Peripheral Blood Lymphocytes Using Interphas
Many cancers arise from gene-environment interactions, where susceptible individ
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Tumor-Targeted Salmonella: Strain Development and Expression of the HSV-tK Effector Gene
Gene therapy approaches to cancer treatment have been limited by the ability of
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Use of Diphenylamine in the Detection of Apoptosis
The diphenylamine assay is a very useful tool in measuring apoptosis by determin
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Diagnosis and Monitoring of AML1-MTG8 (ETO)-Positive Acute Myeloid Leukemia by Qualitative and Real-
Assessing the level of residual disease in leukemia is vital for evaluating pati
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Isolation and Culture of Renal Cancer Cell Lines
Renal cell carcinoma (RCC) represents approximately 2% of all cancers and accoun
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Prognostic Relevance of Angiogenic, Proliferative, and Apoptotic Factors in Lung Carcinomas: A Case
Angiogenesis—the development and formation of new blood vessels—is important in
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Immunohistochemical Diagnostic and Prognostic Markers for Melanoma
Recent studies in our laboratory have identified novel molecular diagnostic and
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Transfection and DNA-Mediated Gene Transfer
The advent of recent technologies such as gene expression microarrays and high-t
