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Genetic Engineering in the Mouse: Tuning TNF/TNFR Expression
With the exponential increase in the number of genes identified by various genom
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Polymeric Nanoparticles for Drug Delivery
The use of biodegradable polymeric nanoparticles (NPs) for controlled drug deliv
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Collagen-Induced Arthritis as a Model for Rheumatoid Arthritis
Collagen-induced arthritis (CIA) is an animal model of rheumatoid arthritis (RA)
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Determination of Cell-Specific Receptor Binding Using a Combination of Immunohistochemistry and In V
Mapping of receptor binding to specific structures, or cells within tissue sampl
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PEGylated Nanocarriers for Systemic Delivery
In this chapter, we outline the protocols for PEGylation of some drug carriers,
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Imaging Metastatic Cell Trafficking at the Cellular Level In Vivo with Fluorescent Proteins
Fluorescent proteins have revolutionized biology, allowing what was formerly inv
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Immortalization of Human Prostate Cells With the Human Papillomavirus Type 16 E6 Gene
A survey of the Medline titles for the years 2000–2001 revealed 125 papers whose
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Transforming Growth Factor-1 as a Novel Marker of Response to Therapy for Renal Cell Carcinoma
Renal cell carcinoma is expected to account for 30,000 new cancer cases and 11,9
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Quantitation of RNA by Ribonuclease Protection Assay
A robust ribonuclease protection assay is described here. In brief, total cellul
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PCR Diagnosis of T-Cell Lymphoma in Paraffin-Embedded Bone Marrow Biopsies
Management of T-cell lymphoma patients requires bone marrow examination for the
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Parental Smoking and Childhood Leukemia
Childhood leukemia is the most common cancer among children, representing 31% of
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Retroviral/Lentiviral Transduction and Transformation Assay
Non-random chromosomal translocations can be found in about half of acute leukae
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Neoadjuvant Endocrine Therapy Models
Neoadjuvant therapy is therapy administered before surgical intervention and whi
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Immunizing Potential of Cytokine-Transduced Tumor Cells
The molecular definition of tumor antigens, costimulatory signals, and the possi
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Clinical and Biological Relevance of Recently Defined Categories of Pulmonary Neoplasia
The clinical management of lung neoplasia now involves considerations of several