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Multiplex Caspase Activity and Cytotoxicity Assays
Multiplexed assay chemistries provide for multiple measurements of cellular para
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Mixture-Based Peptide Libraries for Identifying Protease Cleavage Motifs
All proteases and peptidases are to some extent sequence-specific, in that one o
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Computational Identification of Cancer Susceptibility Loci
The identification of novel cancer susceptibility syndromes and genes from very
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Recent Insights into Drug Resistance in Ovarian Cancer
Ovarian cancer, as used in this review on drug resistance, applies to the study
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Dideoxy DNA sequencing is routinely used in research and, increasingly, in clinical care for the det
Western blotting is utilized to detect and quantify the amount of a specific pro
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DNA Sequencing of Cancer-Related Genes for Biomarker Discovery
Dideoxy DNA sequencing is routinely used in research and, increasingly, in clini
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Biochemical Analysis of the Cell Cycle and Cell Cycle Checkpoints in Transiently Transfected Cells A
It is frequently necessary to examine the biochemical effects of ectopically exp
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The MTT Assay to Evaluate Chemosensitivity
The assessment of the degree or rate of cellular proliferation and cell viabilit
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Polymorphisms of DNA Repair Genes: ADPRT, XRCC1, and XPD and Cancer Risk in Genetic Epidemiology
Many studies have suggested that adenosine diphosphate ribosyl transferase (ADPR
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Immunohistochemical Analysis for hMLH1 and hMSH2 Expression in Colorectal Cancer
Defective DNA mismatch repair (MMR) occurs in the majority of tumors from patien
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Differential Expression of Apoptosis-Associated Genes bax and bcl-2 in Ovarian Cancer
The deregulation of the balance between proliferation and programmed cell death
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Gene Therapy in Melanoma
The identification of genes involved in different biologic functions and in the
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Chemopreventive Therapeutics: Inhalation Therapies for Lung Cancer and Bronchial Premalignancy
Lung cancer is the number one cause of cancer-related death in the US. In 2001,
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Detecting and Modulating the NF-kB Activity in Human Immune Cells: Generation of Human Cell Lines wi
NF-κB plays a pivotal role in immunity and inflammation and is considered to be
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Molecular Genetic Analysis of Flow-Sorted and Microdissected Ovarian Tumor Cells Improved Detection
Study of loss of heterozygosity (LOH) is widely used to identify chromosomal loc