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Different Study Designs in the Epidemiology of Cancer: Case-Control vs. Cohort Studies
It is only since the 1950s that most of the epidemiology studies on cancer have
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Identification of Mutations in the Retinoblastoma Gene
Mutations in the retinoblastoma gene (RBl) predispose to the formation of ocular
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Isolation of Melanoma Cell Subpopulations Using Negative Selection
Melanomas are phenotypically and functionally heterogeneous tumors comprising of
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WT-1 Overexpression in Acute Myeloid Leukemia and Myelodysplastic Syndromes
The Wilms tumor gene was identified as a tumor suppressor gene responsible for a
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Induction of Tumor Cell Apoptosis by TRAIL Gene Therapy
Members of the tumor necrosis factor (TNF) superfamily influence a variety of im
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Topoisomerase I and II Activity Assays
DNA topoisomerases I and II (top1 and top2, respectively) are ubiquitous enzymes
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Fluorescence itIn Situ Hybridization
In situ hybridization describes the annealing of a labeled nucleic acid to compl
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Microsatellite Analysis to Assess Chromosome 18q Status in Colorectal Cancer
Loss of the long arm of chromosome 18 (18q) is one of the most common genetic ch
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Mitochondria Potential, Bax Activation, and Programmed Cell Death
Since the discovery of the key role of cytochrome C in the activation of caspase
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Investigating Macrophage and Malignant Cell Interactions In Vitro
Within most human and murine cancers there is an abundant macrophage population,
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Identification of Protein Interaction Partners by the Yeast Two-Hybrid System
The two-hybrid system is a genetic method to search for and to identify direct i
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Immunity of Lentiviral Vector-Modified Dendritic Cells
Innovative approaches to induce a strong immune response are key to the success
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Cell Cycle and Drug Sensitivity
Induction of tumor cell death by chemotherapeutic modalities often occurs in a c
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Development of Orthotopic Pancreatic Tumor Mouse Models
Genetically engineered mouse models of pancreatic cancer that recapitulate human
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Analysis of Cell Cycle by Flow Cytometry
Described are four widely used procedures to analyze the cell cycle by flow cyto
