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Genetic Testing in Familial Melanoma: Epidemiologic/Genetic Assessment of Risks and Role of CDKN2A A
The first description of familial melanoma in the English literature appeared in
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Overcoming Multidrug Resistance by RNA Interference
The ATP-binding cassette (ABC)-transporter P-glycoprotein (Pgp, also known as AB
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Functional Profiling Methods in Cancer
The introduction of new high-throughput methodologies such as DNA microarrays co
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Design and Testing of Novel Oncolytic Vaccinia Strains
Oncolytic or replication-selective viruses have been used as powerful tools for
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Hereditary Colon Cancer Genes
Colorectal cancer develops as the result of the progressive accumulation of gene
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Xenotransplantation of Breast Cancers
Three experimental systems based on mouse models are currently used to study bre
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Xenograft Models in Immunodeficient Animals: I. Nude Mice: Spontaneous and Experimental Metastasis M
The growth of metastases is the end result of a multistep process in which cance
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Cytogenetic Studies in Hematologic Malignancies: An Overview
The techniques for obtaining chromosomes from phytohemagglutinin (PHA)-stimulate
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Flow Cytometric Analysis of MDM2-Mediated Growth Arrest
Although MDM2, the product of mouse double minute-2 (mdm2 ) gene, or its human h
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Breast Cancer Screening and Biomarkers
Annual screening mammograms have been shown to be cost-effective and are credite
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Comparative Genomic Hybridization and Fluorescence In Situ Hybridization in Chronic Lymphocytic Leuk
The first reported recurring chromosome aberrations in B-cell chronic lymphocyti
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Orthotopic Model of Renal Cell Carcinoma
A human renal cancer was first established in continuous culture in 1962. Curren
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Assaying Cdc25 Phosphatase Activity
To determine the activity of all human Cdc25 phosphatases, two different methods
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Application of Gene Microarrays in the Study of Prostate Cancer
Gene macro- and microarrays have become an increasingly popular tool to investig
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Gene Expression Profiling of Leukemia Stem Cells
Characterization of gene expression programs and pathways important for normal a
