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Design and Testing of Novel Oncolytic Vaccinia Strains
Oncolytic or replication-selective viruses have been used as powerful tools for
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Hereditary Colon Cancer Genes
Colorectal cancer develops as the result of the progressive accumulation of gene
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Xenotransplantation of Breast Cancers
Three experimental systems based on mouse models are currently used to study bre
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Xenograft Models in Immunodeficient Animals: I. Nude Mice: Spontaneous and Experimental Metastasis M
The growth of metastases is the end result of a multistep process in which cance
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Cytogenetic Studies in Hematologic Malignancies: An Overview
The techniques for obtaining chromosomes from phytohemagglutinin (PHA)-stimulate
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Flow Cytometric Analysis of MDM2-Mediated Growth Arrest
Although MDM2, the product of mouse double minute-2 (mdm2 ) gene, or its human h
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Breast Cancer Screening and Biomarkers
Annual screening mammograms have been shown to be cost-effective and are credite
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Comparative Genomic Hybridization and Fluorescence In Situ Hybridization in Chronic Lymphocytic Leuk
The first reported recurring chromosome aberrations in B-cell chronic lymphocyti
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Orthotopic Model of Renal Cell Carcinoma
A human renal cancer was first established in continuous culture in 1962. Curren
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Assaying Cdc25 Phosphatase Activity
To determine the activity of all human Cdc25 phosphatases, two different methods
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Application of Gene Microarrays in the Study of Prostate Cancer
Gene macro- and microarrays have become an increasingly popular tool to investig
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Gene Expression Profiling of Leukemia Stem Cells
Characterization of gene expression programs and pathways important for normal a
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Orthotopic, Syngeneic Mouse Model to Study the Effects of EpithelialStromal Interaction
One of the difficulties in studying ovarian cancer historically has been the lac
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Pharmacogenetic Analysis of Clinically Relevant Genetic Polymorphisms
With the recent publication of the human genome sequence, there has been an expa
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A Simple Method for Profiling miRNA Expression
Here we describe a simple protocol that uses positively charged nylon membrane d
