-
Tumor Suppressor Genes in Lung Cancer
Lung cancer is the number-one cancer killer of both men and women in the United
-
Cell Separations by Flow Cytometry
Flow cytometry has become a standard method for separating individual subsets of
-
Transforming Growth Factor Beta: A Plasma Tumor Marker
Malignant tumors have been known for many years to release proteins or polypepti
-
Strategies for the Use of Site-Specific Recombinases in Genome Engineering
Conventional gene targeting has been very useful in the study of gene function a
-
Molecular Mechanisms of Drug Resistance in Single-Step and Multi-Step Drug-Selected Cancer Cells
Multidrug resistance (MDR) remains one of the key determinants in chemotherapeut
-
In Vitro Model of Spontaneous Mouse OSE Transformation
An in vitro syngeneic model of neoplastic progression of murine ovarian surface
-
Quantitative and Spatial Image Analysis of Tumor and Draining Lymph Nodes Using Immunohistochemistry
Immunohistochemistry is an essential tool for clinical and translational researc
-
Engineering Hot Spots for Affinity Enhancement of Antibodies
The potential of antibodies as magic bullets for targeting therapeutic drugs or
-
Gene Expression Profile Analysis of Tumors
Gene expression profiling is a powerful tool to analyze the complexity of cancer
-
Use of the Polymerase Chain Reaction Technique to Detect the t(14;18) Translocation in Lymphoid Tiss
The t(14;18) (q32;21) chromosomal translocation is characteristic of follicle ce
-
Nanoparticle Characterization for Cancer Nanotechnology and Other Biological Applications
Nanotechnology is actively being used to develop promising diagnostics and thera
-
Direct Kinase Assay Screening for Inhibitors of MAP Kinase
An important convergence point involved in the signal transduction pathways of m
-
Using In Vivo Biopanning for the Development of Radiation-Guided Drug Delivery Systems
This chapter illustrates our protocol for in vivo biopanning using T7 bacterioph
-
Analysis of Growth Properties and Cell Cycle Regulation Using Mouse Embryonic Fibroblast Cells
A balance between proliferation and apoptosis is crucial for cellular homeostasi
-
In Situ Hybridization in Cancer and Normal Tissue
With recent advances in the Human Genome Project and progress in microarray and
