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DNA Immunization as a Means to Generate Antibodies to Proteins
For over a century now, antibodies have proven to be extremely useful reagents i
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Measurement of Estrogen Receptor Status by Immunocytochemistry in Paraffin Wax Sections
The estrogen receptor (ER) status and, to a lesser extent, progesterone receptor
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Quantitative PCR Detection of c-erbB-2 Gene Amplification
The association of c-erbB-2 oncogene amplification and prognostic factors was in
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Identification and Analysis of Precursors to Invasive Pancreatic Cancer
Histologically distinct noninvasive precursor lesions have been recognized in th
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RNA Purification and Quantification Methods
Analysis of gene expression within tumors is frequently performed on the messeng
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Use of siRNA to Study the Function of MDC1 in DNA Damage Responses
Small interfering RNA (siRNA) technology has emerged as a powerful genetic tool
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Complete Array of HOX Gene Expression by RQ-PCR
In mammals the HOX network consists of 39 genes which encode master regulators o
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Production of Plasmid DNA as a Pharmaceutical
Developments in gene therapy, cell therapy, and DNA vaccination require a pharma
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Functional Analysis of Tumor Suppressor Genes in Mice
The utilization of mice as a model for human cancer goes back to the generation
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Microarray-Based Comparative Genomic Hybridization (Array-CGH) as a Useful Tool for Identifying Gene
Alterations in the genome that lead to changes in DNA sequence copy number are a
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Immunoscope Analysis of T-Lymphocytes Infiltrating Melanocytic Tumors
Melanomas are most frequently infiltrated by actively proliferating T-lymphocyte
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The Chick Embryo Metastasis Model
The growth and dissemination of malignant tumors continues to have a devastating
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The Regulation of Tumor Suppressor Genes by Oncogenes
Tumor suppressor genes (TSGs) and oncogenes represent the ying and the yang of c
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Cancer Gene Profiling in Prostate Cancer
Gene profiling and expression analysis using microarrays have made a significant
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Detection and Analysis of DNA Methylation by Pyrosequencing
Pyrosequencing is a “sequencing by synthesis” technique which can be used to qua
