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DNA Methylation and Histone Modifications in Breast Cancer
Breast cancer is caused by progressive genetic alterations and epigenetic change
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Diagnosis and Monitoring of CBFB-MYH11-Positive Acute Myeloid Leukemia by Qualitative and Quantitati
During the last decade, many mutations present in myeloid leukemias have been mo
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Generation and Characterization of p53 Mutant Mice
p53 is one of the most well-characterized members of the tumor suppressor gene f
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G1 and S-Phase Checkpoints, Chromosome Instability, and Cancer
Mitogen-dependent progression through the first gap phase (G1) of the mammalian
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Flow Cytometric Measurement of Cell Proliferation
The simplest guide to cell proliferation that can be obtained by the use of flow
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Incomplete DJH Rearrangements
Analysis of Ig genes in B-cell malignancies has become an essential method in mo
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The Impact of Hepatitis B Virus (HBV) and Hepatitis C Virus (HCV): From Research to Clinical Practic
Hepatic carcinogenesis is a complex process that involves profound alterations o
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Identifying Obstacles to Viral Gene Therapy for Lung Cancer: Malignant Pleural Effusions as a Paradi
We have been investigating intrapleural malignancy as a “proof of concept” clini
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18 Direct Sequencing for Cowden Syndrome Gene PTEN (MMAC1) Mutations
Cowden syndrome is a rare dominantly inherited condition with predisposition to
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UroVysion Multiprobe FISH in Urinary Cytology
Urinary cytology is used in combination with cystoscopy for the diagnosis of pri
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The Polymerase Chain Reaction
The polymerase chain reaction (PCR) has had a significant impact on all aspects
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Analyzing the G2/M Checkpoint
The G2 checkpoint prevents cells from entering mitosis when DNA is damaged, prov
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Mutation of p53 Tumor Suppressor Gene in Hepatocellular Carcinoma
In recent years, the most commonly observed genetic alteration in hepatocellular
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Identifying Genes Related to Chemosensitivity Using Support Vector Machine
In an effort to identify genes involved in chemosensitivity and to evaluate the
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Approaches to Proteomic Analysis of Human Tumors
The involvement of tumor suppressor genes (TSG) in cancer initiation and progres