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Patched, Hedgehog, and Skin Cancer
The Hedgehog signaling pathway plays a key role in directing growth and patterni
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Preparation of Metaphase Chromosomes for Cytogenetic Analysis
The in vitro cultivation of cells and tissues forms an integral part of the work
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Measurement of Reduced Glutathione Using High-Pressure Liquid Chromatography
As outlined in Chapter 8 , glutathione in the intact cell is maintained predomin
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The INK4a/ARF Locus and Human Cancer
This review focuses on the role of the INK4a/ARF locus in human cancer. Several
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c-myb Antisense Oligonucleotide Therapeutics for Hematologic Malignancies
Although improved significantly, conventional treatment of hematologic malignanc
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DNA Methylation Analysis in Human Cancer
Many tumor suppressor genes (such as p16, Rb, VHL, E-cadherin , and hMLH1 ) that
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In Vitro Micronucleus Technique to Predict Chemosensitivity
The study of DNA damage at the chromosome level is an essential part of genetic
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Genes Involved in the Metastatic Cascade of Medullary Thyroid Tumours
The process of how a benign tumour turns invasive and capable to survive in dist
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Mutation Analysis of Cancer Using Automated Sequencing
There are a variety of methods for the detection and definition of mutations in
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Immunodiagnosis of Childhood Malignancies
Diagnosis of childhood malignancies, in particular solid tumors, is an enterpris
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Elimination of Mycoplasma from Infected Cell Lines Using Antibiotics
Although many mycoplasma contaminations of cell cultures remain undetected over
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Molecular Basis of Histone Deacetylase Inhibitors as New Drugs for the Treatment of Inflammatory Dis
Histone deacetylase inhibitors are potent inducers of growth arrest and apoptoti
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Anti-MDR1 Ribozyme Gene Therapy
Multidrug resistance (MDR) in human cancer seriously limits the efficacy of anti
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MicroRNA Profiling Using Fluorescence-Labeled Beads: Data Acquisition and Processing
The discovery of small regulatory RNA molecules during the last years has change
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Cytogenetic Characterization of Tumor Cell Lines
The total number of human tumor cell lines is probably too great to count accura
