-
Detection of the Replication Error Phenotype in Ovarian Cancer-PCR Analysis of Microsatellite Instab
Microsatellites are simple, tandemly repeated DNA sequences that are abundantly
-
Immunohistochemical Assays of Farnesyltransferase Inhibition in Patient Samples
As a result of early reports indicating that farnesylation was required for matu
-
AIDS-Associated Pulmonary Cancers
Neoplastic disease occurs more frequently in immunocompromised patients than in
-
Laser-Capture Microdissection
Laser-capture microdissection is a recently discovered state-of-the-art method t
-
Production and Characterization of Receptor-Specific TNF Muteins
Tumor necrosis factor (TNF) is a pleiotropic cytokine with a wide range of biolo
-
Functional Analysis of the Spindle-Checkpoint Proteins Using an In Vitro Ubiquitination Assay
The spindle checkpoint helps to ensure the fidelity of chromosome segregation du
-
Quality Assurance of Predictive Markers in Breast Cancer
It has been estimated that in 2002, 555,500 Americans will have died of cancer,
-
Development of Rituximab-Resistant B-NHL Clones: An In Vitro Model for Studying Tumor Resistance to
Therapeutic strategies for cancer include chemotherapy, immunotherapy, and radia
-
The Prevention and Genetics of Pancreatic Cancer: A Programmatic Approach
Pancreatic cancer (PC) is typically a fatal disease due to its rapid growth and
-
MRD Detection in B-Cell Non-Hodgkin Lymphomas Using Ig Gene Rearrangements and Chromosomal Transloca
Minimal residual disease (MRD) diagnostics is of high clinical relevance in pati
-
Circumventing Tumor Resistance to Chemotherapy by Nanotechnology
Patient relapse and metastasis of malignant cells is very common after standard
-
Mechanisms of Multidrug Resistance in Cancer
The development of multidrug resistance (MDR) to chemotherapy remains a major ch
-
Syngeneic Murine Metastasis Models: B16 Melanoma
Animal studies are costly, time consuming, and subject to several restrictive re
-
Establishment of Primary Cultures from Ovarian Tumor Tissue and Ascites Fluid
We have refined the technique for isolating and propagating cultures of primary
-
Tumor Markers in Screening for Ovarian Cancer
Tumor markers are used for multiple purposes in clinical care, including screeni
