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Evaluation of Chemosensitivity of Micrometastases with Green Fluorescent Protein Gene-Tagged Tumor M
The chemosensitivity of micrometastasis is an important factor in therapeutic ap
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Development of a Cytokine-Modified Allogeneic Whole Cell Pancreatic Cancer Vaccine
The management of patients with pancreatic cancer is a multidisciplinary approac
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Use of RNA Aptamers for the Modulation of Cancer Cell Signaling
Aptamers are in vitro evolved molecules that bind to target proteins with high a
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Clinically Relevant Metastatic Breast Cancer Models to Study Chemosensitivity
Metastatic disease, notably to the lungs, liver, bone, and brain, is the most co
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Virus Production for Clinical Gene Therapy
Gene therapy is becoming increasingly relevant for the treatment of prominent hu
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Cell Cycle Checkpoint Control Mechanisms That Can Be Disrupted in Cancer
Maintenance of genomic integrity is essential to avoid cellular transformation,
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Expression Analysis of Homeobox Genes in Leukemia/Lymphoma Cell Lines
Homeobox genes code for transcription factors which have a strong impact on cell
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Antisense Oligonucleotide Inhibitors of MDM2 Oncogene Expression
Antisense therapy represents a novel genetic-based therapeutic approach, initiat
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Use of Nanoparticles for Targeted, Noninvasive Thermal Destruction of Malignant Cells
Shortwave (MHz range) radiofrequency (RF) energy is nonionizing, penetrates deep
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Digital Single-Nucleotide Polymorphism Analysis for Allelic Imbalance
Digital single-nucleotide polymorphism (SNP) analysis is developed to amplify a
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Single-Chain Fv-Based Affinity Purification of the Cellular Stress Protein gp96 for Vaccine Developm
Cellular stress proteins like the classical heat-shock proteins (HSPs) hsp70 (1
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Isolation of Circulating MicroRNAs from Microvesicles Found in Human Plasma
Intact miRNAs can be isolated from the circulation in significant quantities des
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Epigenetics of Solid Cancer Stem Cells
Epigenetics is an emerging science that can help to explain carcinogenesis. The
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Enhanced Mismatch Mutation Analysis: Simultaneous Detection of Point Mutations and Large Scale Rearr
We present the routine diagnostic application of EMMA (Enhanced Mismatch Mutatio
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Rapid Identification of Chromosomes Using Primed In Situ Labeling (PRINS)
Primed in situ labeling (PRINS) was introduced by Koch and colleagues (1 ) for t