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Molecular-Targeted Therapy for Cancer and Nanotechnology
In order to stop malignant tumor growth, >90% of a critical biochemical pathw
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Adenovirus-Mediated Wild-Type p53 Gene Transfer into Head and Neck Cancers
Mutation of the p53 tumor-suppressor gene is recognized as one of the most commo
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Assaying for BRAF V600E in Tissue and Blood in Melanoma
The BrafV600E mutation has been detected in patients with metastatic melanoma, c
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Assays for Neoplastic Cell Enrichment in Bone Marrow Samples
Most hematological malignancies have clonal cells that reside in the bone marrow
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Development of Drug-Resistant Models
The observation that tumors are capable of developing resistance to anticancer a
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Modeling Pancreatic Cancer in Animals to Address Specific Hypotheses
Multiple experimental approaches have been employed to study exocrine pancreatic
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Introduction
Like most cytogeneticists, I have been informed by well-meaning colleagues at re
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Retroviral Transfer of the Herpes Simplex Virus-Thymidine Kinase (HSV-tK) Gene for the Treatment of
Gene therapy is defined as the alteration of the genetic material of a cell with
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Gene Therapy for Antitumor Vaccination
Tumor immunotherapy depends on the interactions between the host, the tumor, and
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Detection of Prostate-Cancer Cells in Blood and Bone Marrow by RT-PCR
As cancer treatment options broaden, there is a corresponding increase m the nee
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Photoacoustic Tomography for Imaging Nanoparticles
Nanotechnology is the key to a new, noninvasive photoacoustic imaging technique
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Activation of Caspase Protease During Apoptosis in Ovarian Cancer Cells
As a genetically controlled program, apoptosis has important roles in a variety
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Flow Cytometric Methods for Detection and Quantification of Apoptosis
The accumulation of cells characteristic of neoplastic disease results from the
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Isolation and Culture of Ovarian Cancer Cells and Cell Lines
Ovarian carcinomas show considerable heterogeneity of origin, both in terms of s
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Phase I Clinical Trial of Locoregional Administration of the Oncolytic Adenovirus ONYX-015 in Combin
Despite many advances in cancer therapy, metastatic disease continues to be incu
