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Cytogenetic and Genetic Studies in Solid Tumors: Background
Solid tumors comprise approx 95% of all malignancies, but account for only a lit
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Generation of Recombinant Immunotoxins for Specific Targeting of Tumor-Related Peptides Presented by
Specificity in the immune system is dictated and regulated by specific recogniti
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MicroRNA Northern Blotting, Precursor Cloning, and Ago2-Improved RNA Interference
Aberrant expression of microRNAs (miRNAs) and processing defects in their biogen
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Determination of Telomerase Activity and Telomere Length
Telomerase is an enzyme that has been attracting much attention in recent years
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Helicobacter -Based Mouse Models of Digestive System Carcinogenesis
Animal models are necessary to reproduce the complex host, microbial and environ
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Mutational Screening of hMLH1 and hMSH2 that Confer Inherited Colorectal Cancer Susceptibility Using
Hereditary nonpolyposis colorectal cancer syndrome (HNPCC) is primarily due to h
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Mammographic Density: A Heritable Risk Factor for Breast Cancer
The appearance of the breast on mammography varies among women, reflecting varia
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Xenograft Models in Immunodeficient Animals: II. The Use of SCID Mice in Metastasis Research: Breast
Metastasis is a multistep phenomenon, and all steps have to be successfully and
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Hereditary Breast and Ovarian Cancer Genes
Breast cancer affects one out of every 10 women in industrialized countries, and
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Generation and Analysis of Brca1 Conditional Knockout Mice
Germline mutations of the breast tumor suppressor gene BRCA1 predispose women to
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Autoantibodies Against Cancer Antigens
With the identification of tumor antigens, the host immune response to various t
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Proteomics in the Analysis of Prostate Cancer
High-throughput DNA analysis has generated a wealth of information on predicted
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Gene Amplification of c-erbB-2 Detected by FISH
In 1981, a novel transforming gene called neu, related to, but distinct from, th
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Emerging Clinical Issues in Melanoma in the Molecularly Targeted Era
The standard of care of patients with malignant melanoma is dramatically changin
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Primary Explant Cultures of Adult and Embryonic Pancreas
The developmental plasticity of adult pancreas is evidenced by the ability to un