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Gene Amplification of c-erbB-2 Detected by FISH
In 1981, a novel transforming gene called neu, related to, but distinct from, th
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Emerging Clinical Issues in Melanoma in the Molecularly Targeted Era
The standard of care of patients with malignant melanoma is dramatically changin
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Primary Explant Cultures of Adult and Embryonic Pancreas
The developmental plasticity of adult pancreas is evidenced by the ability to un
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Regulation of NF-B by Oncoproteins and Tumor Suppressor Proteins
The transcription factor nuclear factor-κB (NF-κB) has been demonstrated to cont
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Localization of Cyclooxygenase-2 Protein Expression in Lung Cancer Specimens by Immunohistochemical
Cyclooxygenase-2 (COX-2) inhibitors comprise a group of compounds that show prom
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MTT Growth Assays in Ovarian Cancer
The MTT (3-[4,5-dimethylthiazol-2yl]-2,5-diphenyl tetrazolium bromide) growth as
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Apoptosis Detection by DNA Analysis
Apoptosis is a series of controlled sequential events resulting in cell death. T
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Xenopus Cell-Free Extracts to Study the DNA Damage Response
Cell-free systems derived from Xenopus eggs represent a powerful tool, intermedi
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Anchorage-Independent Growth of Prostate Cancer Stem Cells
Prostate cancer is a major health concern in the Western world. Prostate cancer
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Mutation Detection in Colorectal Cancers: Direct Sequencing of DNA Mismatch Repair Genes
The detection of unknown mutations has proved complex and time consuming, and th
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Gene Expression Microarrays
New methods have been developed for determining and monitoring gene expression l
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Detection of Apoptosis in Renal Cell Carcinoma
Apoptosis is a selective process of programmed cell death that plays an importan
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I1307K Mutation Detection by Allele-Specific PCR in Familial Colorectal Cancer
Familial colorectal cancer (FCC) is a hereditary form of colorectal cancer that
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Reciprocal Subtraction Differential RNA Display (RSDD): An Efficient Technology for Cloning Differen
Identification of differentially expressed genes is an essential step in compreh
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Invasion and Motility Assays
A key feature of malignant cells is their capacity to invade surrounding tissue
