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Linking the Kaposi's Sarcoma-Associated Herpesvirus (KSHV/HHV-8) to Human Malignancies
In 1994, the Kaposi's sarcoma-associated herpesvirus (KSHV/HHV-8) was identi
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Real-Time Cytotoxicity Assays
Validation of new therapeutic targets calls for the advance in innovative assays
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Single-Strand Conformation Polymorphism Mutation Analysis of the p53 Gene
Single-strand conformation polymorphism (SSCP) is a rapid and convenient procedu
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MRD Detection in Acute Lymphoblastic Leukemia Patients Using Ig/TCR Gene Rearrangements as Targets f
Minimal residual disease (MRD) diagnostics has proven to be clinically relevant
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Flow Cytometric DNA Analysis of Human Cancers and Cell Lines
Measurement of DNA content was one of the first applications to be developed in
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Assessment of TNFα-Induced Endothelial Damage Through the Loss of Its Barrier Function
Tumor necrosis factor α (TNFα) appears to be the main mediator causing the syste
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Transformation of the Human Ovarian Surface Epithelium with Genetically Defined Elements
Success in in vitro transformation of primary cells from the human ovarian surfa
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Molecular Epidemiology of DNA Repair Genes in Bladder Cancer
Bladder cancer is a common disease, whose major risk factors include smoking and
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Reverse-Phase Protein Microarrays for Theranostics and Patient Tailored Therapy
Analysis of the genome provides important information about the somatic genetic
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Analysis of HSV Oncolytic Virotherapy in Organotypic Cultures
Tumor-selective replication-competent viral vectors, such as oncolytic herpes si
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Analysis of Telomerase Activity and Telomere Function in Cancer
Telomeres are the structures at the ends of chromosomes, composed of repetitive
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Murine Animal Model
Experimental animal models are available for the development of new treatment. M
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Purification of Recombinant p53 from Sf9 Insect Cells
We describe a method for purifying recombinant p53 from baculovirus infected cel
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Detection of the Content and Activity of the Transcription Factor AP-1 in a Multistage Skin Carcinog
Investigation of transcription factor activity in animal tissue during the early
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Functional Analysis of Human BRCA2 Variants Using a Mouse Embryonic Stem Cell-Based Assay
We describe here a comprehensive and reliable assay to test the functional signi
