DNA Polymerases (EC 2.7.7.7)
DNA polymerases catalyze the synthesis of DNA molecules from monomeric deoxynucl
DNA polymerases catalyze the synthesis of DNA molecules from monomeric deoxynucleotide triphosphate units. This definition encompasses those enzymes classed as DNA-dependent DNA polymerases (EC 2.7.7.7, which require both a DNA template strand and a DNA primer to which the monomeric units can be added), reverse transcriptases (EC 2.7.7.49, RNA-dependent DNA polymerases that utilize an RNA template), and terminal deoxynucleotidyl transferases (EC 2.7.7.31, which require no template). This chapter will consider only DNA-dependent DNA polymerases (EC 2.7.7.7, DNA nucleotidyltransferases, DNA-directed).