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细胞技术

Xenografting and Harvesting Human Ductal Pancreatic Adenocarcinomas for DNA Analysis

2025-03-14 细胞技术 加入收藏
Xenotransplantation (xenografting) of primary cancers or cancer cell lines into

Xenotransplantation (xenografting) of primary cancers or cancer cell lines into immunodeficient mice is a commonly used technique to assess tumor growth in response to a variety of experimental agents. When primary pancreatic cancers are xenografted, cancer cells proliferate in the mouse, but the human stroma does not. This growth pattern enables facile genetic analysis of cancer genetics profiles without the contamination of admixed stromal cells typical of primary cancers.

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