Anti-c-erb1B2 Ribozyme for Gene Therapy of Breast Cancer

The application of antioncogene ribozyme in the gene therapy of breast cancer by means of recombinant adenoviral vector is dicussed in this chapter. We have shown that recombinant adenovirus encoding anti-cerbB2 ribozyme inhibited the breast cancer cell growth in vivo efficiently (1 ,2 ). We will talk about the detailed protocol here.