Use of Peptide Nucleic Acids (PNAs) for Genotyping by Solution and Surface Methods
Peptide nucleic acids (PNAs) are synthetic oligonucleotide analogues based on a
Peptide nucleic acids (PNAs) are synthetic oligonucleotide analogues based on a pseudopeptide backbone that bind complementary DNA or RNA with high affinity and specificity. In this chapter, three PNA-based genotyping assays are described: PCR clamping, fluorescence-based recognition, and microarray platform. The first two methods are performed in solution, while the microarray method uses a solid surface.
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Preparation of Metal-Containing Peptide Nucleic Acid Bioconjugates on the Solid Phase
Peptide nucleic acids (PNAs) are a class of artificial DNA/R...
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Synthesis, Characterization, and Evaluation of Radiometal-Containing Peptide Nucleic Acids
Peptide nucleic acids (PNAs) have very attractive properties...
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