Less common disorders:W
DISEASE AND CAUSESPATHOPHYSIOLOGYSIGNS AND SYMPTOMSWegener's granulomatosisC
| DISEASE AND CAUSES | PATHOPHYSIOLOGY | SIGNS AND SYMPTOMS |
| Wegener's granulomatosis | ||
| Localized granulomatous inflammation of upper or lower respiratory tract mucosa may progress to generalized necrotizing granulomatous vasculitis and glomerulonephritis. |
|
| Wilson's disease | ||
| Defective mobilization of copper from hepatocellular lysosomes for excretion via the bile allows excessive copper retention in the liver, brain, kidneys, and corneas, leading to tissue necrosis and subsequent hepatic and neurologic disorders. | Kayser-Fleischer ring:
|
| Wiskott-Aldrich syndrome | ||
| Deficiency in both B-cell and T-cell function allows for susceptibility to infection. Metabolic defect in platelet synthesis causes production of small, short-lived platelets resulting in thrombocytopenia. | In newborn:
|
相关文章
