CD18分子

CD18 分子   CD18 常用单克隆抗体或代号： MHM23;(LFA组b 链,integrin b 2,CR3) 主要表达细胞： Leu [AS] 分子质量(kDa)和结构： gp95 功    能： ICAM- 1(CD54)、ICAM- 2(CD102)、ICAM- 3、C3bi配体,粘附,调理吞噬   CD18 Forms the beta 2 chain of CD11a, b, c (leukocyte adhesion molecule) Important for adhesion and signaling in the hemaoietic system (see CD11 a-c above) Leukocyte Adhesion Deficiency (LAD-1) caused by CD18 defect coding for common b2 subunit; patients suffer from recurrent infections Positive staining: leukocytes