CD19分子

CD19 分子   CD19 常用单克隆抗体或代号： B4,Leu12 主要表达细胞： B,Pre,FDC [B] 分子质量(kDa)和结构： gp90(IgSF) 功    能： 与CD21、CD81组成复合物,调节B细胞活化   CD19 Response regulator that plays a dominant role in establishing signaling thresholds for antigen receptors and other surface receptors on B cells; also regulates B cell development, activation and differentiation CD19 antibody inhibits B cell activation from anti-immunoglobulin Coreceptor with CD21 Earliest B cell antigen in fetal tissue Positive staining (normal): Pre B, B cells; first B cell antigen after HLA-DR, follicular dendritic cells Negative staining: plasma cells