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  • Overcoming Multidrug Resistance in Cancer: Clinical Studies of P-Glycoprotein Inhibitors

    Overcoming Multidrug Resistance in Cancer: Clinical Studies of P-Glycoprotein Inhibitors

    Chemotherapy remains the mainstay in the treatment and management of many cancer

    2025-03-20 75
  • Overview of Novel Anticancer Drug Targets

    Overview of Novel Anticancer Drug Targets

    There has been an explosion in the number of potential molecular targets that ca

    2025-03-20 73
  • PCR Analysis of Microsatellite Instability

    PCR Analysis of Microsatellite Instability

    Microsatellites are simple, tandemly repeated DNA sequences which are abundantly

    2025-03-20 86
  • MHC 四聚体助力细胞治疗基础研究:CTL 表位筛选

    MHC 四聚体助力细胞治疗基础研究:CTL 表位筛选

    据统计,2015 年,我国癌症新发人数为 429.2 万。死亡人数 281.4 万,平均 5 年生存率 36.9%。肺癌、胃癌、肝癌、食管癌占到总数的 57%。

    2025-03-20 83
  • Human Recombinant Fab Antibodies with T-Cell Receptor-Like Specificities Generated from Phage Displa

    Human Recombinant Fab Antibodies with T-Cell Receptor-Like Specificities Generated from Phage Displa

    In this chapter we describe efficient procedures for the construction, expressio

    2025-03-20 71
  • Markers for Anti-cytotoxic T-lymphocyte Antigen 4 (CTLA-4) Therapy in Melanoma

    Markers for Anti-cytotoxic T-lymphocyte Antigen 4 (CTLA-4) Therapy in Melanoma

    Therapeutic strategies that block Cytotoxic T lymphocyte antigen-4 (CTLA-4) enha

    2025-03-20 84
  • Measuring Cyclin-Dependent Kinase Activity

    Measuring Cyclin-Dependent Kinase Activity

    The activity of cyclin-dependent kinases (CDKs) lies at the heart of cell cycle

    2025-03-20 71
  • Transgenic Animal Models

    Transgenic Animal Models

    Cancer is a prevalent and poorly understood disease in human populations. It is

    2025-03-20 71
  • Diagnosis and Monitoring of Chronic Myeloid Leukemia by Qualitative and Quantitative RT-PCR

    Diagnosis and Monitoring of Chronic Myeloid Leukemia by Qualitative and Quantitative RT-PCR

    Real-time quantitative reverse-transcription polymerase chain reaction (RQ-PCR)

    2025-03-20 83
  • galactosidase assay for cells transfected with pSV- -Galactosidase Vector

    galactosidase assay for cells transfected with pSV- -Galactosidase Vector

    Chen-Ming Fan Lab,Carnegie Institute of WashingtonPrepare cell lysate as you wou

    2025-03-20 74
  • Tailoring Kinetics of Antibodies Using Focused Combinatorial Libraries

    Tailoring Kinetics of Antibodies Using Focused Combinatorial Libraries

    Antibodies have been used extensively for diagnostic applications for decades. A

    2025-03-20 72
  • 用LIPO2000转染HepG2细胞的问题

    用LIPO2000转染HepG2细胞的问题

    乡乡问:最近本人在做HepG2细胞的转染,转染的是GFP质粒,按照LIPO2000的说明书使用后,发现细胞的死亡很严重,24h时差不多死了一半。而且我在转染前细

    2025-03-20 84
  • 腺病毒能在293中复制吗?

    腺病毒能在293中复制吗?

    腺病毒可以在293A细胞中进行转录,表达并可进行包装复制出大量高滴度病毒。293T是一种逆转录包装表达细胞,我做过也可进行表达,但还没有具体鉴定表达后的病毒是否

    2025-03-20 79
  • Cytogenetics in Myelodysplastic Syndromes

    Cytogenetics in Myelodysplastic Syndromes

    Cytogenetic information in patients with myelodysplastic syndrome (MDS) is impor

    2025-03-20 55
  • Detection and Quantification of Leukemia-Specific Rearrangements

    Detection and Quantification of Leukemia-Specific Rearrangements

    A number of leukemia-specific chromosomal translocations have been identified th

    2025-03-20 59