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Sequencing of the Tumor Suppressor Gene TP 53
The tumour suppressor gene, TP 53 (commonly also called p53 ) has multiple, impo
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Advances in Adjuvant Therapy: Potential for Prognostic and Predictive Biomarkers
Melanoma is the third most common skin cancer but accounts for the majority of s
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Molecular Breakpoint Analysis of Chromosome Translocations in Cancer Cell Lines by Long Distance Inv
With conventional cytogenetic screening by fluorescence in situ hybridization (F
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Role of Xenobiotic Metabolic Enzymes in Cancer Epidemiology
The cause of the majority of cancers is poorly understood albeit multifactorial.
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Altered Surface Markers in Lung Cancer: Lack of Cell-Surface Fas/APO-1 Expression in Pulmonary Adeno
Bronchogenic carcinoma is the leading cause of cancer-related mortality, with th
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Construction and Analysis of Multiparameter Prognostic Models for Melanoma Outcome
The outcome of Stage II melanoma is uncertain. Despite that 10-year melanoma-spe
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Evaluating Dietary Compounds in Pancreatic Cancer Modeling Systems
With the establishment of outstanding rodent models of pancreatic neoplasia and
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Analysis of Tumor-Associated Mucin Glycotopes by Western Transfer Methods
In mucins, glycosylation is complex and the most predominant posttranslational m
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Use of Minicircle Plasmids for Gene Therapy
A large number of cancer gene therapy clinical trials are currently being perfor
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Combined Adenoviral Transfer of Tumor Suppressor and Cell-Cycle Genes for Tumor-Cell Apoptosis
The loss of control over the cell cycle and the disruption of cascade mechanisms
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Interphase Cytogenetics in Paraffin-Embedded Ovarian Tissue
Interphase cytogenetics using formalin-fixed/paraffin-embedded tissue is now a w
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Polymeric Micelles: Polyethylene Glycol-Phosphatidylethanolamine (PEG-PE)-Based Micelles as an Examp
One of the renowned nanosized pharmaceutical carriers for delivery of poorly sol
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Small-Cell Lung Cancer (SCLC) Cell Adhesion on E- and P-Selectin Under Physiological Flow Conditions
Hematogenous metastasis is still a poorly understood phenomenon. The rate-limiti
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Analysis of Apoptosis in Tissue Sections
The recognition over the past decade that apoptosis represents a critical elemen
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High-Resolution Quantitative Methylation Analysis of MicroRNA Genes Using Pyrosequencing
MicroRNA (miRNA) genes have been shown to perform a crucial role in breast cance