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Storage of Cell Lines
The successful storage of cell lines depends upon many factors, including the co
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Assessment of Local Proteolytic Milieu as a Factor in Tumor Invasiveness and Metastasis Formation: I
Matrix invasion by a tumor cell requires the degradation of components in the ex
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Bisulfite Methylation Analysis of Tumor Suppressor Genes in Prostate Cancer from Fresh and Archival
It is now well established that, in addition to genetic changes that may include
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Developing Classifiers for the Detection of Cancer Using Multi-Analytes
The development of a successful classifier from multiple predictors (analytes) i
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Assaying the Spindle Checkpoint in the Budding Yeast Saccharomyces cerevisiae
The spindle checkpoint is assayed in Saccharomyces cerevisiae using several crit
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Detection of Rearrangements in the bcl-2 Gene Using the Polymerase Chain Reaction
Described here is a simple polymerase chain reaction (PCR) method for detecting
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Meta-analysis of Cancer Gene-Profiling Data
DNA microarray profiles are plagued by the issue of large number of variables bu
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Demonstration of a Germinal Center Immunophenotype in Lymphomas by Immunocytochemistry and Flow Cyto
The germinal center plays an important role in the pathogenesis of B-cell lympho
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Humanization of Monoclonal Antibodies by CDR Grafting
The discovery of the process for making rodent monoclonal antibodies (MAbs) 26 y
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Detection of Aberrant Glycosylation in Breast Cancer Using Lectin Histochemistry
Lectins are naturally occurring, carbohydrate-binding molecules that can be isol
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Detection of Telomerase Activity by PCR-Based Assay
Telomeres are distal ends of human chromosomes composed of tandem repeats of the
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Epigenetics in Ovarian Cancer
Ovarian cancer is the most lethal gynecological cancer. Due to few early symptom
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Use of DNA Fingerprinting to Detect Genetic Rearrangements in Human Cancer
The polymerase chain reaction (PCR) has revolutionized the isolation and analysi
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Analyzing the Function of Tumor Suppressor Genes Using a Drosophila Model
With 1600 eyes, a pair of antennae, 6 legs, and an open circulatory system, the
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Clinical Implications of p53 Mutations in Lung Cancer
The p53 tumor-suppressor gene plays a crucial role in the cellular response to s
