-
Clinical Implications of Epigenetic Alterations in Human Thoracic Malignancies: Epigenetic Alteratio
Besides known genetic aberrations, epigenetic alterations have emerged as common
-
Generation of Genetically Modified Embryonic Stem Cells for the Development of Knockout Mouse Animal
The aim of our lab is to understand the contributions made by cell adhesion mole
-
Genome-Wide Methylation Analysis
The disruption and alteration of genomic methylation patterns is a hallmark of c
-
High-Throughput Mutation Screening Using a Single Amplification Condition
Numerous innovative and high-throughput techniques have been established to iden
-
Methods in Cancer Epigenetics and Epidemiology
Cancer cells are characterized by epigenetic dysregulation, including global gen
-
Generation of Immortal Human Prostate Cell Lines for the Study of Prostate Cancer
Prostate cancer is the most common male cancer in the United States, as well as
-
In Vivo Particle-Mediated Gene Transfer for Cancer Therapy
During the past several years, particle-mediated delivery techniques have been d
-
In Vitro and In Vivo Apoptosis Detection Using Membrane Permeant Fluorescent-Labeled Inhibitors of C
Apoptosis detection methodology is an ever evolving science. The caspase family
-
Transposable Elements as Plasmid-Based Vectors for Long-Term Gene Transfer into Tumors
A primary limitation to using nonviral vectors for cancer gene therapy is transi
-
Energy Balance, Physical Activity, and Cancer Risk
This chapter posits that cancer is a complex and multifactorial process as demon
-
Genetically Modified Clostridium for Gene Therapy of Tumors
Many murine and human tumors contain hypoxic or necrotic regions in which the ox
-
Homogeneous, Bioluminescent Proteasome Assays
Protein degradation is mediated predominantly through the ubiquitin–proteasome p
-
Adhesion Signaling Through Integrins
Tumor cell interactions with the local microenvironment influence a range of cel
-
RT-PCR Analysis of Breakpoints Involving the MLL Gene Located at 11q23 in Acute Leukemia
Chromosome rearrangements of chromosome 11 at band 1 1q23 are detected in a high
-
Factors Affecting Immunohistochemical Evaluation of Biomarker Expression in Neoplasia
Archival paraffin blocks frequently are studied to evaluate the expression of bi
