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Relationship of EGFR Signal-Transduction Modulation by Tyrosine Kinase Inhibitors to Chemosensitivit
Epidermal growth factor receptor (EGFR) is a transmembrane glycoprotein of 170 k
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Dissection of Tumor and Host Cells from Metastasized Organs for Testing Gene Expression Directly Ex
The interaction between tumor and host cells determines to a large extent the ou
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Imaging Specific Cell Surface Protease Activity in Living Cells Using Reengineered Bacterial Cytotox
The scarcity of methods to visualize the activity of individual cell surface pro
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Molecular Epidemiology of Human Cancer Risk: Gene-Environment Interactions and p53 Mutation Spectrum
Epidemiology has identified several etiological factors in lung cancer, of which
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Purification and Analysis of Checkpoint Protein Complexes From Saccharomyces cerevisiae
The DNA damage-dependent checkpoint of Saccharomyces cerevisiae is a paradigm fo
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Magnetic Resonance Imaging of Metastases in Xenograft Mouse Models of Cancer
Magnetic resonance imaging (MRI) of small animals has emerged as a valuable tool
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Targeting of Nanoparticles: Folate Receptor
Nanoparticulate medicines offer the advantage of allowing delivery of large quan
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Laser-Assisted Microdissection and Isolation of DNA and RNA
One of the major challenges in molecular analysis of breast cancer specimens is
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Induced Nitric Oxide Synthase as a Major Player in the Oncogenic Transformation of Inflamed Tissue
Nitric oxide (NO) is a free radical that is involved in the inflammatory process
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Caspase-3 Activation is a Critical Determinant of Genotoxic Stress-Induced Apoptosis
A number of methods have been developed to identify the cells that undergo apopt
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Flow Cytometric MRD Detection in Selected Mature B-Cell Malignancies
The quantification of submicroscopic minimal residual disease (MRD) after therap
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Immunomagnetic Cell Separation
In metastasis research, it may sometimes be necessary to separate populations of
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Molecular Analysis of Cancer: An Overview
Cancer is a complex disease occurring as a result of a progressive accumulation
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Detecting Mismatch Repair Defects in Myeloma
Defects in the mismatch repair system are associated with a microsatellite unsta
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Gene Expression Profiling to Characterize Anticancer Drug Sensitivity
This chapter presents a protocol for using cDNA microarrays to acquire gene expr
