Login
欢迎浏览恩派尔生物资料网
我要投稿 请登录 免费注册 安全退出

您现在的位置是: 首页 > 实验方法 > 细胞技术

细胞技术

Expression of Human Collagenase I (MMP-1) andTIMP-1 in a Baculovirus-Based Expression System

2025-03-06 细胞技术 加入收藏
Resident cells of tissues are capable of secreting an array of structurally rela

Resident cells of tissues are capable of secreting an array of structurally related zinc endopeptidases known as matrix metalloproteinases (MMPs). They initiate the degradation of the surrounding macromolecules of the extracellular matrix (ECM), mostly proteoglycans and specific types of collagen. ECM degradation presumably contributes to the initial phase of tissue remodeling inherent to the physiological processes of morphogenesis, angiogenesis, involution of the uterus, bone resorption, inflammation, and wound healing. The aberrant activity of MMPs has been found to be involved in a variety of pathological processes, e.g., rheumatoid joint destruction, corneal ulceration, metastasis of tumor cells, and various genetic diseases (1 ,2 ).

文章底部广告位

文章评论

加载中~