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MicroRNA Profiling in Ovarian Cancer
The evaluation of microRNA profiles has represented one of the first approaches
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PTEN and Cancer
Genetic evidence strongly suggested that a tumor suppressor was located on chrom
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Isolation and Culture of Leukemia Cell Lines
The availability of continuous human leukemia cell lines as a rich resource of a
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TP53, hChk2, and the Li-Fraumeni Syndrome
In 1969 Li and Fraumeni (1 ,2 ) reported a systematic epidemiologic study of the
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Caspase Activity Assays
Caspase activity assays in multi-well plate formats represent powerful tools for
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Selection of Cytochrome P450 Genes for Use in Prodrug Activation-Based Cancer Gene Therapy
Prodrug activation-based cancer gene therapy is a molecular strategy to improve
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Electrophoretic Mobility Shift Analysis of the DNA Binding of Tumor Suppressor Gene Products
Central to the tumor suppressor activity of certain proteins is the ability to i
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Application of SNP Genotype Arrays to Determine Somatic Changes in Cancer
Genetic abnormalities in leukaemia range from single gene defects to chromosomal
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Detection of K-ras Mutations by a Microelectronic DNA Chip
The increased knowledge of the human genome, thanks to its sequencing and to the
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Integrating Multiple Clinical Tests to Increase Predictive Power
Clinical tests provide information that can be used by statistical methods to ma
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Generation and Application of Phospho-specific Antibodies for p53 and pRB
The functions of many proteins are likely to be regulated by phosphorylation. Th
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Tumor Vascular Therapy With TNF: Critical Review on Animal Models
To study tumor therapeutic treatment modalities, whether from a clinical, precli
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Quantitation of CD39 Gene Expression in Pancreatic Tissue by Real-Time Polymerase Chain Reaction
Within the past decade, the field of gene expression analysis has constantly evo
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Authentication of Cancer Cell Lines by DNA Fingerprinting
The requirement for authentication of cell lines has a history almost as long as
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Tumor-Infiltrating Lymphocytes and Their Significance in Melanoma Prognosis
The role of the tumor-infiltrating lymphocyte (TIL) and its relationship to prog
