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Electrophoretic Mobility Shift Analysis of the DNA Binding of Tumor Suppressor Gene Products
Central to the tumor suppressor activity of certain proteins is the ability to i
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Application of SNP Genotype Arrays to Determine Somatic Changes in Cancer
Genetic abnormalities in leukaemia range from single gene defects to chromosomal
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Detection of K-ras Mutations by a Microelectronic DNA Chip
The increased knowledge of the human genome, thanks to its sequencing and to the
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Integrating Multiple Clinical Tests to Increase Predictive Power
Clinical tests provide information that can be used by statistical methods to ma
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Generation and Application of Phospho-specific Antibodies for p53 and pRB
The functions of many proteins are likely to be regulated by phosphorylation. Th
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Tumor Vascular Therapy With TNF: Critical Review on Animal Models
To study tumor therapeutic treatment modalities, whether from a clinical, precli
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Quantitation of CD39 Gene Expression in Pancreatic Tissue by Real-Time Polymerase Chain Reaction
Within the past decade, the field of gene expression analysis has constantly evo
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Authentication of Cancer Cell Lines by DNA Fingerprinting
The requirement for authentication of cell lines has a history almost as long as
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Tumor-Infiltrating Lymphocytes and Their Significance in Melanoma Prognosis
The role of the tumor-infiltrating lymphocyte (TIL) and its relationship to prog
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Aerosol Gene Therapy for Metastatic Lung Cancer Using PEI-p53 Complexes
Inactivation of p53wt, a tumor-suppressor gene, has been observed in a majority
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Molecular Analysis of the von Hippel-Lindau Disease Gene
Von Hippel-Lindau (VHL) disease is an autosomal dominant disorder that predispos
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Recent Advances and Dilemmas in the Radiotherapeutic Management of Locally Advanced Non-Small Cell L
During the 1990s, thoracic radiotherapy (RT) combined with chemotherapy was acce
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Generation of Recombinant Multimeric Antibody Fragments for Tumor Diagnosis and Therapy
Single chain recombinant antibody fragments can multimerise to provide high bind
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Detecting DNA Methylation Using the Methylated CpG Island Amplification and Microarray Technique
Methylated CpG island amplification and microarray (MCAM) is a two-color array t
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Targeted Chemotherapy in Drug-Resistant Tumors, Noninvasive Imaging of P-Glycoprotein-Mediated Funct
Multidrug resistance (MDR) mediated by overexpression of P-glycoprotein (Pgp) is