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Solving Problems in Multiplex FISH
Over the last 15 yr, advances in molecular biology have allowed improvements in
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Marker Utility for Combination Therapy
Melanoma is a heterogeneous disease for which monotherapies are likely to fail i
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Compartmentalized Protein Kinase C Activation in Ovarian Carcinoma Cells
Protein kinase C (PKC), a family of phospholipid-dependent serine/threonine kina
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Overexpression of PRV-1 Gene in Polycythemia Rubra Vera and Essential Thrombocythemia
The polycythemia rubra vera 1 gene (PRV-1 ), a member of the urokinase-type plas
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Molecular Diagnosis of Acute Myeloid Leukemia with Maturation, FAB-Type M2
Nonrandom chromosome abnormalities frequently are seen in particular subtypes of
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Neurosphere Culture and Human Organotypic Model to Evaluate Brain Tumor Stem Cells
The brain tumor stem cell (BTSC) hypothesis is based on the premise that there i
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Matrix Metalloproteinases and Their Inhibitors
Matrix metalloproteinases (MMPs) are a group of 16 enzymes that are capable of d
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Laser Microdissection Sample Preparation for RNA Analyses
Gene expression analysis provides an insight into the unique and defining biomol
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Functional Analysis of the Antimitogenic Activity of Tumor Suppressors
Loss of tumor suppressors contributes to numerous cancer types. Many, but not al
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NanoparticleAptamer Conjugates for Cancer Cell Targeting and Detection
Aptamers are DNA or RNA oligonucleotide sequences that selectively bind to their
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Gene Expression Profile Analysis of Lymphomas
Through the genome-wide characterization of a cell type’s transcriptome, gene ex
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Quantitative, Fluorescence-Based In-Situ Assessment of Protein Expression
As companion diagnostics grow in prevalence and importance, the need for accurat
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Detection of TNF and TNF Receptor mRNA in Cells and Tissues
We describe a semiquantitative reverse transcriptase polymerase chain reaction (
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Manual Microdissection
The new opportunities of modern assays of molecular biology can only be exploite
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Measurements of Phospholipases A2, C, and D (PLA2, PLC, and PLD): In Vitro Microassays, Analysis of
In order to be properly divisible, the cell membrane has to be remodeled and int
