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Matrix Metalloproteinases and Their Inhibitors
Matrix metalloproteinases (MMPs) are a group of 16 enzymes that are capable of d
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Laser Microdissection Sample Preparation for RNA Analyses
Gene expression analysis provides an insight into the unique and defining biomol
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Functional Analysis of the Antimitogenic Activity of Tumor Suppressors
Loss of tumor suppressors contributes to numerous cancer types. Many, but not al
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NanoparticleAptamer Conjugates for Cancer Cell Targeting and Detection
Aptamers are DNA or RNA oligonucleotide sequences that selectively bind to their
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Gene Expression Profile Analysis of Lymphomas
Through the genome-wide characterization of a cell type’s transcriptome, gene ex
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Quantitative, Fluorescence-Based In-Situ Assessment of Protein Expression
As companion diagnostics grow in prevalence and importance, the need for accurat
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Detection of TNF and TNF Receptor mRNA in Cells and Tissues
We describe a semiquantitative reverse transcriptase polymerase chain reaction (
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Manual Microdissection
The new opportunities of modern assays of molecular biology can only be exploite
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Measurements of Phospholipases A2, C, and D (PLA2, PLC, and PLD): In Vitro Microassays, Analysis of
In order to be properly divisible, the cell membrane has to be remodeled and int
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Simultaneous Flow Cytometric Detection of DNA and Cellular Protein Molecules
Flow cytometry (FCM) is a sophisticated technique for rapid simultaneous analysi
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Zebrafish as a Model for Pancreatic Cancer Research
Elucidation of basic mechanisms that regulate pancreatic organogenesis may help
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Development of a Scoring System to Screen for BRCA1/2 Mutations
Selection for genetic testing for pathogenic mutations in BRCA1 and BRCA2 is an
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Primary Mouse Endothelial Cell Culture for Assays of Angiogenesis
The growth of new blood vessels, known as angiogenesis, is a dynamic but highly
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Methods for Chemoprotection and Chemosensitization: MDR-1 For Chemoprotection Using Retroviruses to
Surgery, radiation therapy, and chemotherapy have been applied to the curative t
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Fluorescence In Situ Hybridization and Comparative Genomic Hybridization
This chapter discusses the complementary methodologies of fluorescence in situ h
