-
Meta-analysis of Cancer Gene-Profiling Data
DNA microarray profiles are plagued by the issue of large number of variables bu
-
Demonstration of a Germinal Center Immunophenotype in Lymphomas by Immunocytochemistry and Flow Cyto
The germinal center plays an important role in the pathogenesis of B-cell lympho
-
Humanization of Monoclonal Antibodies by CDR Grafting
The discovery of the process for making rodent monoclonal antibodies (MAbs) 26 y
-
Detection of Aberrant Glycosylation in Breast Cancer Using Lectin Histochemistry
Lectins are naturally occurring, carbohydrate-binding molecules that can be isol
-
Detection of Telomerase Activity by PCR-Based Assay
Telomeres are distal ends of human chromosomes composed of tandem repeats of the
-
Epigenetics in Ovarian Cancer
Ovarian cancer is the most lethal gynecological cancer. Due to few early symptom
-
Use of DNA Fingerprinting to Detect Genetic Rearrangements in Human Cancer
The polymerase chain reaction (PCR) has revolutionized the isolation and analysi
-
Analyzing the Function of Tumor Suppressor Genes Using a Drosophila Model
With 1600 eyes, a pair of antennae, 6 legs, and an open circulatory system, the
-
Clinical Implications of p53 Mutations in Lung Cancer
The p53 tumor-suppressor gene plays a crucial role in the cellular response to s
-
Detection of Apoptosis in Ovarian Cells In Vitro and In Vivo Using the Annexin V-Affinity Assay
The ability of a cell to undergo apoptosis is crucial during development, tissue
-
Drug Delivery Approaches for Ovarian Cancer Therapy
Tumor-specific drug delivery represents a challenging issue that restricts the c
-
Current Applications of Nanotechnology for Magnetic Resonance Imaging of Apoptosis
Apoptosis, or programmed cell death, is a morphologically and biochemically dist
-
Genetic Manipulation of Yeast to Identify Genes Involved in Regulation of Chemosensitivity
Fission and budding yeast have been regarded as valuable tools for studying seve
-
Analysis of Cell Cycle Progression and Genomic Integrity in Early Lethal Knockouts
Owing to their importance in normal cell division, DNA damage checkpoint and rep
-
Multidrug Resistance in Cancer
It is becoming increasingly clear that the proliferation of human tumours is dri
