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A Method for Conducting Highly Sensitive MicroRNA In Situ Hybridization and Immunohistochemical Anal
Profiling experiments in whole tissue biopsies have linked altered expression of
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Cloning of Immunoglobulin Chromosomal Translocations by Long-Distance Inverse Polymerase Chain React
Many subtypes of B-cell malignancy are characterized by chromosomal translocatio
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Clinical Application of Tissue and Serum Markers in Breast Cancer
How different the practice of oncology would become if physicians could predict
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Novel Approaches to Screen for Anticancer Drugs Using Saccharomyces cerevisiae
The development of anticancer drugs has relied primarily on two traditional appr
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Prioritizing Candidate Genetic Modifiers of BRCA1 and BRCA2 Using a Combinatorial Analysis of Global
Epidemiological evidence from different studies has shown that genes harboring s
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Abrogation of the RB-p16Tumor Suppressor Pathway in Human Lung Cancer
There is compelling evidence that human lung cancers are characterized by disrup
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Challenges in Experimental Modeling of Ovarian Cancerogenesis
Ovarian cancer is a complex disease, with unclear origins, complicated, multiste
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Optimal Molecular Profiling of Tissue and Tissue Components: Defining the Best Processing and Microd
Isolation of well-preserved pure cell populations is a prerequisite for sound st
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Co-immunoprecipitation of Tumor Suppressor Protein-Interacting Proteins
Tumor suppressor proteins, like most proteins, require interacting with other pr
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Detection of Chromosomal Deletions by Microsatellite Analysis
Microsatellites are tandem repeats of simple sequence, 2–6 bp, that occur abunda
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Immunocytochemical Detection and Characterization of Individual Micrometastatic Tumor Cells
Early hematogenous spread of cancer cells must be regarded as major cause for th
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Microsatellite Instability Testing
Microsatellites are tandem repeats of simple sequences that occur abundantly and
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Ultrasound Techniques for the Detection of Tumors and Metastases in Small Animals
Small animals are widely used for the identification of new therapeutic targets
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Reconstruction of Geno-Phenotypic Evolutionary Sequences from Intracellular Patterns of Molecular Ab
In this chapter we describe an approach to the analysis of human tumors that emp
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Cytogenetics of Solid Tumours
The study of chromosome abnormalities in solid tumours provides valuable informa
