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In Vivo Particle-Mediated Gene Transfer for Cancer Therapy
During the past several years, particle-mediated delivery techniques have been d
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In Vitro and In Vivo Apoptosis Detection Using Membrane Permeant Fluorescent-Labeled Inhibitors of C
Apoptosis detection methodology is an ever evolving science. The caspase family
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Transposable Elements as Plasmid-Based Vectors for Long-Term Gene Transfer into Tumors
A primary limitation to using nonviral vectors for cancer gene therapy is transi
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Energy Balance, Physical Activity, and Cancer Risk
This chapter posits that cancer is a complex and multifactorial process as demon
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Genetically Modified Clostridium for Gene Therapy of Tumors
Many murine and human tumors contain hypoxic or necrotic regions in which the ox
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Homogeneous, Bioluminescent Proteasome Assays
Protein degradation is mediated predominantly through the ubiquitin–proteasome p
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Adhesion Signaling Through Integrins
Tumor cell interactions with the local microenvironment influence a range of cel
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RT-PCR Analysis of Breakpoints Involving the MLL Gene Located at 11q23 in Acute Leukemia
Chromosome rearrangements of chromosome 11 at band 1 1q23 are detected in a high
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Factors Affecting Immunohistochemical Evaluation of Biomarker Expression in Neoplasia
Archival paraffin blocks frequently are studied to evaluate the expression of bi
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Storage of Cell Lines
The successful storage of cell lines depends upon many factors, including the co
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Assessment of Local Proteolytic Milieu as a Factor in Tumor Invasiveness and Metastasis Formation: I
Matrix invasion by a tumor cell requires the degradation of components in the ex
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Bisulfite Methylation Analysis of Tumor Suppressor Genes in Prostate Cancer from Fresh and Archival
It is now well established that, in addition to genetic changes that may include
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Developing Classifiers for the Detection of Cancer Using Multi-Analytes
The development of a successful classifier from multiple predictors (analytes) i
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Assaying the Spindle Checkpoint in the Budding Yeast Saccharomyces cerevisiae
The spindle checkpoint is assayed in Saccharomyces cerevisiae using several crit
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Detection of Rearrangements in the bcl-2 Gene Using the Polymerase Chain Reaction
Described here is a simple polymerase chain reaction (PCR) method for detecting
