目前已发表文章中RNAi设计的片段综述
Gene (Ref)Accession #Position from ATGGene Target (Comments)Cell Line Testedß-ac
Gene (Ref) | Accession # | Position from ATG | Gene Target (Comments) | Cell Line Tested |
ß-actin (1) | NM_001101 | 972-994 | aatgaagatcaagatcattgc | Human HeLa |
gamma-actin (1) | NM_001614 | 8-30 | aagagatcgccgcgctggtca | Human HeLa |
AIB1 (estrogen receptor coactivator) (22) | AAAGACUCCUUAGGACCGCUU | Ishikawa | ||
Apaf-1 (31) | 978-998 | AATTGGTGCACTTTTACGTGA | IMR90E1 | |
ARC21 (1) | AF006086 | 181-203 | aagaatgaagctgataggacc | Human HeLa |
ATR interacting protein (4) | AF451323 | 254-274 | AAGGTCCACAGATTATTAGAT | Human HeLa |
ATR interacting protein (4) | AF451323 | 464-484 | CTAGAGGAACAGAGAAGATCACA | Human HeLa |
ATR interacting protein (4) | AF451323 | 867-887 | AAGAAGAGGCCCAGAAAAGCT | Human HeLa |
Bcr-abl (32) | AAGCAGAGUUCAAAAGCCCUU | TonB, K562, hematopoetic cells | ||
Brc-abl (32) | AAAGCAGAGUUCAAAAGCCCU | TonB, K562, hematopoetic cells | ||
beta-tubulin- mouse neuronal (21) | AF312873 | AAGACAGAGCCAAGUGGACUC | Mouse P19 | |
Bruton's tyrosine kinase (Btk) (33) | NM_000061 | 1682-1700 | AAUUGGUAAACGAUCAAGGAG | RBL-2H3, WEHI-231, NALM-6 |
Bruton's tyrosine kinase (Btk) (33) | NM_000061 | 895-913 | AAGGGAAAGAAGGAGGUUUCA | RBL-2H3, WEHI-231, NALM-6 |
Bruton's tyrosine kinase (Btk) (33) | NM_000061 | 518-536 | AAGAAGCUUAAAACCUGGGAG | RBL-2H3, WEHI-231, NALM-6 |
Casein Kinase I epsilon and delta (CKI-epsilon and CKI-delta) (17) | 520-538 | AACUGGGGAAGAAGGGCAACC | HEK293 | |
Caspase 1 (34) | 191-211 | AAGGGGCACAGGCATGCCAAA | IMR90E1A | |
Caspase 2 (34) | 94-114 | AAACAGCTGTTGTTGAGCGAA | IMR90E1A | |
hCdc2 (24) | 125-147 | HeLa | ||
Cdc14A (23) | 89-109 | GCACAGTAAATACCCACTATT | HeLa | |
cdk1 (1) | NM_001786 | 125-147 | aaggggttcctagtactgcaa | Human HeLa |
CENP-E (1) | NM_001813 | 944-966 | aaactcttactgctctccagt | Human HeLa |
CHO1 (20) | 138-156 | AAGGUCAGUAAUACAACGGUG | CHO | |
corin, mouse (12) | AACCACCGCCCUCCGUGCA | HL-5 and 293 | ||
Cyclin B1 (5) | J03166 | 199-217 | CTCGTACAGCCTTGGGAGACA | Xenopus embryo |
Cyclin B2 (5) | J03167 | 252-270 | ATGTTAAGACTAAGCATGTAC | Xenopus embryo |
cytoplasmic dynein 1 heavy chain (1) | U53530 | 509-531 | aaggccaaggaggcgctggaa | Human HeLa |
DIP13-alpha (DCC interacting protein) (25) | AAGUGCAGCAACACACCUGAC | DLD1 | ||
DIP13-beta (DCC interacting protein) (25) | AAGCAGCACCUCUCCUCCCUU | DLD1 | ||
Dishevelled (hDv-1 and hDv-3) (16) | AACAAGATCACCTTCTCCGAG | A293 | ||
hDv-2 (16) | AACTTTGAGAACATGAGCAAC | A293 | ||
Eg5 (1) | NM_004523 | 1547-1569 | aactggatcgtaagaaggcag | Human HeLa |
emerin (1) | NM_000117 | 628-650 | aaccgtgctcctggggctggg | Human HeLa |
eve (11) | AACUCCUUGAACGGCAGCCGC | Drosophila embryos | ||
hFbw7 (cyclin E ubiquitination) (26) | 713-735 | see reference | HeLa | |
Fortilin (35) | 121-141 | AAGGUAACAUUGAUGACUCGC | U2OS | |
GalTII (galactosyltransferase II) (27) | 65-87 | AAGCACGCGACGCUGGCGCGC | HeLa | |
GalTII (galactosyltransferase II) (27) | 461-482 | AAGGCGGACGACGACUCCUUC | HeLa | |
GAS41 (1) | NM_006530 | 327-349 | aagacctgtaaccctgtatca | Human HeLa |
Hec-1 (36) | NM_006101 | 1517-1539 | HeLa-S3 | |
HPV E6 (38) | AAGAGGUAUAUGACUUUGCUU | CaSKi, SiHa, NDF, HCT116 | ||
HPV E7 (38) | AAAGGAGGAUGAAAUAGAUGG | CaSKi, SiHa, NDF, HCT116 | ||
HtrA2 (28) | AAAACGGCUCAGGAUUCGUGG | U2OS | ||
HtrA2 (28) | AAGGGGAGTTTGTTGTTGCCA | U2OS | ||
HtrA2 (28) | AAGCTTTCCCGATGTTCAGCA | |||
keratin 18 (1) | NM_000224 | 1154-1176 | aagatggcgaggactttaatc | Human HeLa |
Kinase interacting stathmin (hKIS) (39) | 160-180 | AAGCAGTTCTTGCCGCCAGGA | HEK293 | |
Kinase interacting stathmin (mKIS) (39) | 160-180 | AAGCAGTTCCTGCCTCGGGGA | HEK293 | |
lamin A (13) | NM019390 | 260-280 | GAAGCAGCUUCAGGAUGAGAU | Human HeLa S3 |
lamin A (19) | AAGGACCUGGAGGUCUGCUG | Hep3B | ||
lamin A/C (1) | NM_005572 | 608-630 | aactggacttccagaagaaca (90% reduction; 2) | Human HeLa |
lamin B1 (1) | NM_005573 | 672-694 | aacgcgcttggtagaggtgga | Human HeLa |
lamin B2 (1) | M94362 | 1457-1479 | aagaggaggaggaagccgagt | Human HeLa |
LAP2 (1) | NM_003276 | 37-59 | aaagacaagttgaagagtgag | Human HeLa |
Mad1 (41) | AF083811 | 1843-1865 | See reference | HeLa-S3 |
Mammalian septin (MSF) (44) | AF189712 | 472-492 | See reference |